ESR1 Mutated Metastatic Breast Cancer Market and Epidemiology 2032: Treatment Market, Therapies, FDA Approval, Epidemiology & Forecast by DelveInsight | Sanofi, Sun Pharma, Pfizer, Arvinas, Zenopharm

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ESR1 Mutated Metastatic Breast Cancer Market and Epidemiology 2032: Treatment Market, Therapies, FDA Approval, Epidemiology & Forecast by DelveInsight | Sanofi, Sun Pharma, Pfizer, Arvinas, Zenopharm

May 15
09:58 2024
ESR1 Mutated Metastatic Breast Cancer Market and Epidemiology 2032: Treatment Market, Therapies, FDA Approval, Epidemiology & Forecast by DelveInsight | Sanofi, Sun Pharma, Pfizer, Arvinas, Zenopharm
The ESR1 Mutated Metastatic Breast Cancer Market Forecast report offers an in-depth understanding of the ESR1 Mutated Metastatic Breast Cancer, historical and forecasted epidemiology as well as the ESR1 Mutated Metastatic Breast Cancer market trends in the 7MM.

ESR1 Mutated Metastatic Breast Cancer Market and Epidemiology 2032: Treatment Market, Therapies, Companies, FDA Approvals, Epidemiology and Forecast by DelveInsight | Radius Pharma/ Menarini Group, Pfizer, G1 Therapeutics, Sanofi, Sun Pharma, Advanced Research Company, Zenopharm, Arvinas, Sermonix Pharma, H3 Biomedicine

DelveInsight’s “ESR1 Mutated Metastatic Breast Cancer Market Insights, Epidemiology, and Market Forecast-2032″ report offers an in-depth understanding of the ESR1 Mutated Metastatic Breast Cancer, historical and forecasted epidemiology as well as the ESR1 Mutated Metastatic Breast Cancer market trends in the United States, EU4 (Germany, Spain, Italy, France) the United Kingdom and Japan.

 

To Know in detail about the ESR1 Mutated Metastatic Breast Cancer market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; ESR1 Mutated Metastatic Breast Cancer Market Forecast

 

Some of the key facts of the ESR1 Mutated Metastatic Breast Cancer Market Report: 

  • The ESR1 Mutated Metastatic Breast Cancer market size was valued approximately USD 1,300 million in 2022 and is anticipated to grow with a significant CAGR during the study period (2019-2032)

  • In the EU4 nations, Germany boasted the largest market size for ESR1-mutated Metastatic Breast Cancer, while Spain had the smallest market size, amounting to approximately USD 40 million in 2022.

  • ORSERDU (elacestrant) received approval in the United States on January 27, 2023, for the treatment of advanced or metastatic breast cancer in postmenopausal women or adult men with hormone receptor-positive (ER+), HER2-negative (HER2-), and ESR1-mutated disease that has progressed following at least one prior endocrine therapy.

  • In 2022, the total diagnosed prevalent population of metastatic breast cancer with ESR1 mutations in the seven major markets (7MM) was roughly 50,000. It is anticipated that this number will rise during the study period from 2019 to 2032.

  • Throughout the study period from 2019 to 2032, Germany had the highest number of cases of ESR1-mutated HR+ metastatic breast cancer among the EU4 countries and the UK, followed by France. Conversely, Spain reported the lowest number of cases compared to the other EU4 countries and the UK.

  • According to DelveInsight estimates, in Japan, approximately 150,000 cases of breast cancer were in the early stage, constituting about 94% of the total, while around 9,000 cases were in the distant or metastatic stage, representing approximately 6% in 2022.

  • In 2022, there were roughly 19,000 diagnosed prevalent cases of ESR1-mutated metastatic breast cancer in the US. It is anticipated that these cases will see an increase over the study period.

  • DelveInsight estimates indicate that the total diagnosed prevalent cases of hormone receptor-positive (HR+) breast cancer in the seven major markets (7MM) amounted to approximately 1 million in 2022. It is anticipated that this figure will rise over the study period from 2019 to 2032.

  • In 2022, the estimated total number of metastatic breast cancer cases in the United States was around 150,000. According to DelveInsight’s analysis, it is projected that these cases will experience an increase by 2032.

  • Future treatments (First-line) like Giredestrant + Palbociclib, Amcenestrant + Palbociclib, and Camizestrant (AZD9833) + Palbociclib have the potential to significantly alter the ESR1 Mutated Metastatic Breast Cancer market

  • Key ESR1 Mutated Metastatic Breast Cancer Companies: AstraZeneca, Sermonix Pharmaceuticals, Sun Pharma Advanced Research Company, Radius Pharmaceuticals/ Menarini Group, Pfizer, G1 Therapeutics, Sanofi, Sun PharmaAdvanced Research Company, Zenopharm, Arvinas, Sermonix Pharmaceuticals, H3 Biomedicine/ Eisai, Roche, and others

  • Key ESR1 Mutated Metastatic Breast Cancer Therapies: Camizestrant (AZD9833), Lasofoxifene, SCO-120, Elacestrant (RAD1901), Ibrance (Palbociclib), Amcenestrant, Rintodestrant (G1T48), G1 Therapeutics, ZB716, ARV-471, Lasofoxifene, H3B-6545, Giredestrant(RG6171, GDC9545), and others

  • The ESR1 Mutated Metastatic Breast Cancer epidemiology based on Treatment Line-specific Cases analyzed that in 2021 out of the total diagnosed prevalent cases of ESR1 Mutated Metastatic Breast Cancer, in the United States, 72% were from the first-line

  • The ESR1 Mutated Metastatic Breast Cancer market is expected to surge due to the disease’s increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage ESR1 Mutated Metastatic Breast Cancer pipeline products will significantly revolutionize the ESR1 Mutated Metastatic Breast Cancer market dynamics.

 

ESR1 Mutated Metastatic Breast Cancer Overview

ESR1 mutated metastatic breast cancer refers to a subtype of breast cancer where mutations occur in the estrogen receptor 1 (ESR1) gene. The ESR1 gene encodes the estrogen receptor alpha, a protein that plays a critical role in breast cancer growth and progression by responding to estrogen signals. Mutations in the ESR1 gene can lead to changes in the estrogen receptor protein, rendering it more active and resistant to hormonal therapies like tamoxifen or aromatase inhibitors.

 

Get a Free sample for the ESR1 Mutated Metastatic Breast Cancer Market Report:

https://www.delveinsight.com/report-store/esr1-mutated-metastatic-breast-cancer-market

 

ESR1 Mutated Metastatic Breast Cancer Epidemiology

The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

 

ESR1 Mutated Metastatic Breast Cancer Epidemiology Segmentation:

The ESR1 Mutated Metastatic Breast Cancer market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into:

  • Total Prevalence of ESR1 Mutated Metastatic Breast Cancer

  • Prevalent Cases of ESR1 Mutated Metastatic Breast Cancer by severity

  • Gender-specific Prevalence of ESR1 Mutated Metastatic Breast Cancer

  • Diagnosed Cases of Episodic and Chronic ESR1 Mutated Metastatic Breast Cancer

 

Download the report to understand which factors are driving ESR1 Mutated Metastatic Breast Cancer epidemiology trends @ ESR1 Mutated Metastatic Breast Cancer Epidemiology Forecast

 

ESR1 Mutated Metastatic Breast Cancer Drugs Uptake and Pipeline Development Activities

The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the ESR1 Mutated Metastatic Breast Cancer market or expected to get launched during the study period. The analysis covers ESR1 Mutated Metastatic Breast Cancer market uptake by drugs, patient uptake by therapies, and sales of each drug. 

Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.

The report also covers the ESR1 Mutated Metastatic Breast Cancer Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

 

ESR1 Mutated Metastatic Breast Cancer Therapies and Key Companies

  • Elacestrant (RAD1901): Radius Pharmaceuticals/ Menarini Group

  • Ibrance (Palbociclib): Pfizer

  • Amcenestrant: Sanofi

  • Rintodestrant (G1T48): G1 Therapeutics

  • G1 Therapeutics: Sun PharmaAdvanced Research Company

  • ZB716: Zenopharm

  • ARV-471: Arvinas

  • Lasofoxifene: SermonixPharmaceuticals

  • H3B-6545: H3 Biomedicine/ Eisai

  • Giredestrant(RG6171, GDC9545): Roche

 

Discover more about therapies set to grab major ESR1 Mutated Metastatic Breast Cancer market share @ ESR1 Mutated Metastatic Breast Cancer Treatment Market

 

ESR1 Mutated Metastatic Breast Cancer Market Strengths

  • ORSERDU is the first endocrine innovation in 20 years specifically targeting ESR1 mutations in ER+, HER2−, advanced, or metastatic breast cancer patients with disease progression following at least one line of endocrine therapy. 

  • ESR1 mutations are common in breast cancer, and research focuses on understanding their mechanisms and developing targeted therapies.

  • Combination therapies have shown promise in treatingESR1-mutant breast cancer, which could improve outcomes for patients

 

ESR1 Mutated Metastatic Breast Cancer Market Opportunities

  • There is a need for new ET agents with strong and durable activity in heavily treated patients, including after standard-of-care first-line therapy with CDK4/6 inhibitors and in those withESR1mutations

  • Advances in genomics and precision medicine could lead to more personalized treatment options for patients withESR1mutations

  • Clinical trials investigating new therapies or combinations of therapies could improve patient outcomes 

  • An improved understanding of the mechanisms behindESR1mutationscould lead to the development of more effective targeted therapies

 

Scope of the ESR1 Mutated Metastatic Breast Cancer Market Report

  • Study Period: 2019–2032

  • Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]

  • Key ESR1 Mutated Metastatic Breast Cancer Companies: AstraZeneca, Sermonix Pharmaceuticals, Sun Pharma Advanced Research Company, Radius Pharmaceuticals/ Menarini Group, Pfizer, G1 Therapeutics, Sanofi, Sun PharmaAdvanced Research Company, Zenopharm, Arvinas, Sermonix Pharmaceuticals, H3 Biomedicine/ Eisai, Roche, and others

  • Key ESR1 Mutated Metastatic Breast Cancer Therapies: Camizestrant (AZD9833), Lasofoxifene, SCO-120, Elacestrant (RAD1901), Ibrance (Palbociclib), Amcenestrant, Rintodestrant (G1T48), G1 Therapeutics, ZB716, ARV-471, Lasofoxifene, H3B-6545, Giredestrant(RG6171, GDC9545), and others

  • ESR1 Mutated Metastatic Breast Cancer Therapeutic Assessment: ESR1 Mutated Metastatic Breast Cancer current marketed and ESR1 Mutated Metastatic Breast Cancer emerging therapies

  • ESR1 Mutated Metastatic Breast Cancer Market Dynamics: ESR1 Mutated Metastatic Breast Cancer market drivers and ESR1 Mutated Metastatic Breast Cancer market barriers 

  • Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies

  • ESR1 Mutated Metastatic Breast Cancer Unmet Needs, KOL’s views, Analyst’s views, ESR1 Mutated Metastatic Breast Cancer Market Access and Reimbursement 

 

To know more about ESR1 Mutated Metastatic Breast Cancer companies working in the treatment market, visit @ ESR1 Mutated Metastatic Breast Cancer Clinical Trials and Therapeutic Assessment

 

Table of Contents 

1. ESR1 Mutated Metastatic Breast Cancer Market Report Introduction

2. Executive Summary for ESR1 Mutated Metastatic Breast Cancer

3. SWOT analysis of ESR1 Mutated Metastatic Breast Cancer

4. ESR1 Mutated Metastatic Breast Cancer Patient Share (%) Overview at a Glance

5. ESR1 Mutated Metastatic Breast Cancer Market Overview at a Glance

6. ESR1 Mutated Metastatic Breast Cancer Disease Background and Overview

7. ESR1 Mutated Metastatic Breast Cancer Epidemiology and Patient Population

8. Country-Specific Patient Population of ESR1 Mutated Metastatic Breast Cancer 

9. ESR1 Mutated Metastatic Breast Cancer Current Treatment and Medical Practices

10. ESR1 Mutated Metastatic Breast Cancer Unmet Needs

11. ESR1 Mutated Metastatic Breast Cancer Emerging Therapies

12. ESR1 Mutated Metastatic Breast Cancer Market Outlook

13. Country-Wise ESR1 Mutated Metastatic Breast Cancer Market Analysis (2019–2032)

14. ESR1 Mutated Metastatic Breast Cancer Market Access and Reimbursement of Therapies

15. ESR1 Mutated Metastatic Breast Cancer Market Drivers

16. ESR1 Mutated Metastatic Breast Cancer Market Barriers

17.  ESR1 Mutated Metastatic Breast Cancer Appendix

18. ESR1 Mutated Metastatic Breast Cancer Report Methodology

19. DelveInsight Capabilities

20. Disclaimer

21. About DelveInsight

 

About DelveInsight 

DelveInsight is a leading Healthcare Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.

It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate the business growth and overcome challenges with a practical approach.

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